Literature Summary

DKA and Cerebral Edema:

How often do patients with DKA present with cerebral edema?

What is the mortality risk of cerebral edema?

What is the pathophys of cerebral edema?

Which is a better rescue hyperosmolar therapy, mannitol or hypertonic saline (HTS)?

Should we hyperventilate pts with DKA cerebral edema for neuroprotection?

Should we limit fluid administration in pts with DKA cerebral edema?

 

Should we administer NaHCO3 in pts with DKA cerebral edema and/or severe acidosis?

Should we increase insulin infusion rate if acidosis or hyperglycemia not correcting quickly?

Should we have a DKA evidence-based pathway in place?

Sources