Transfusions

PRBC's

Interesting Facts

Types of PRBC's

When to Transfuse

From Valentine SL et al, PCCM 2018

How to Transfuse

Plasma

How To Transfuse


Platelets

How to Transfuse


Cryoprecipitate

How to Transfuse:

TEG Interpretation

Courtesy of Richard Pierce, MD

Courtesy of Richard Pierce, MD

Complications

Immediate Reactions

Delayed Reactions

From: Weinstein, American Society of Hematology, 2012 Clinical Practice Guide on Red Blood Cell Transfusion

Massive Transfusion

UM Massive Transfusion Protocol

Massive Transfusion Pediatric Protocol- University of Michigan

References

1) J. Lacroix, P.C. Hébert, J.H. Hutchison, et al.: Transfusion strategies for patients in pediatric intensive care units. N Engl J Med. 356:1609-1619 2007

2) J. Cholette, J. Rubenstein, K. Powers: Cyanotic children undergoing open heart surgery do not appear to benefit from higher hemoglobin levels: Results of a restrictive v liberal RBC transfusion strategy. Crit Care Med. 37:A434 2009

3) Holland LL, Brooks JP. Toward rational fresh frozen plasma transfusion: Theeffect of plasma transfusion on coagulation test results. Am J Clin Pathol. 2006 Jul;126(1):133-9.

4) J. Krishnan, W. Morrison, S. Simone, A. Ackerman:Implications of thrombocytopenia and platelet course on pediatric intensive care unit outcomes. Pediatr Crit Care Med. 9:502-505 2008

5) .S.J. Slitchter: Relationship between platelet count and bleeding risk in thrombocytopenic patients. Transf Med Rev. 18:153-167 2004

6.  Lacroix J, Hébert PC, Fergusson DA, Tinmouth A, Cook DJ, Marshall JC, Clayton L, McIntyre L, Callum J, Turgeon AF, Blajchman MA, Walsh TS, Stanworth SJ, Campbell H, Capellier G, Tiberghien P, Bardiaux L, van de Watering L, van der Meer NJ, Sabri E, Vo D; ABLE Investigators and the Canadian Critical Care Trials Group. Age of Transfused Blood in Critically Ill Adults. N Engl J Med. 2015 Mar 17.PubMed PMID: 25776801.

7. Transfusion Presentation by Kevin Kuo based on Dr. Alan Doctor's Open Pediatrics "Rethinking Transfusions"

8. Karam O, Demaret P, Shefler A, Leteurtre S, Spinella PC, Stanworth SJ, TucciM; Canadian Critical Care Trials Group (CCCTG); Pediatric Acute Lung Injury andSepsis Investigators (PALISI); BloodNet; PlasmaTV Investigators. Indications and Effects of Plasma Transfusions in Critically Ill Children. Am J Respir Crit Care Med. 2015 Jun 15;191(12):1395-402.