PICU Endocrine Issues

Adrenal Insufficiency

Cortisol Physiology

Figure 1: The HPA Axis

Assessment of Adrenal Insufficiency

Causes of Adrenal Insufficiency


Figure 2: Relative Steroid Potencies



Thyroid Dysfunction

Sick Euthyroid Syndrome


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13) Macrae D, Grieve R, Allen E, Sadique Z, Morris K, Pappachan J, Parslow R,Tasker RC, Elbourne D; CHiP Investigators. A randomized trial of hyperglycemic control in pediatric intensive care. N Engl J Med. 2014 Jan 9;370(2):107-18.